Abstract: For the first time, the wood anatomy of Tetraclinis articulata (Vahl) Masters has been studied using representative samples from its natural distribution area in Spain, in Sierra de Cartagena (Region of Murcia). Mature wood was collected from five individuals representative of the forest stand and their anatomy was compared with other genera of the Cupressaceae. Axial tracheids without helical thickenings, low homogeneous rays, cupressoid pits and the absence of normal axial resin canals are characteristic features of this monotypic genus, as they are of most other Cupressaceae genera. An obvious warty layer separates this wood from the genera sharing its territory (Cupressus and Juniperus) and its semi-spherical, slightly anastomosed warts distinguish it from other, geographically distant genera (Actinostrobus and Callitris). The presence of traumatic axial resin canals is reported for the first time and supports the occurrence of this feature outside the Pinaceae. The wood anatomical diversity within the clade comprising Tetraclinis, Microbiota and Platycladus, as reconstructed by molecular analysis, is discussed.